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Nivolumab for the salvage treatment of desperate germ cell tumor: A case report.

Melek S AksunE UcgulTaha Koray SahinDeniz Can GuvenS Aksoy
Published in: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners (2020)
There are limited treatment options in platinum-refractory germ cell tumors. Recently, immune checkpoint inhibitors tried in this setting with some success in especially non-seminomatous GCTs. We see a good response and prolonged benefit with the use of nivolumab in our patient. Further research including prospective studies on the use of immune checkpoint inhibitors in platinum-resistant testicular cancer can further delineate the role of immunotherapy.
Keyphrases
  • germ cell
  • papillary thyroid
  • squamous cell
  • combination therapy
  • childhood cancer
  • case control
  • replacement therapy