Association between computed tomography perfusion and the effect of intravenous alteplase prior to endovascular treatment in acute ischemic stroke.
Jan W HovingHenk van VoorstDaan PeerlingsJasper D DaemsMiou S KoopmanAnke WoutersManon KappelhofNatalie E LeCouffeKilian Maurizio TreurnietAgnetha A E BruggemanLeon A RinkelIdo R van den WijngaardJonathan M CoutinhoA V D LugtHenk A MarqueringYvo B W E M RoosCharles B L M MajoieBart J Emmernull nullPublished in: Neuroradiology (2023)
In directly admitted patients with limited CTP-estimated ischemic core volumes who presented within 4.5 h after symptom onset, CTP parameters did not statistically significantly alter the treatment effect of IVT prior to EVT. Further studies are needed to confirm these results in patients with larger core volumes and more unfavorable baseline perfusion profiles on CTP imaging.