Parathyroid Hormone Secretion and Receptor Expression Determine the Age-Related Degree of Osteogenic Differentiation in Dental Pulp Stem Cells.

Shilpa BhandiAhmed AlkahtaniRodolfo RedaMohammed MashyakhyNezar Boreak Prabhadevi C Maganur Satish VishwanathaiahDeepak MehtaNishant VyasVikrant R Patil A Thirumal Raj Luca Testarelli Shankaragouda Patil

Published in: Journal of personalized medicine (2021)

The therapeutic quality of dental pulp stem cells is largely based on their ability to retain their stemness characteristics. This study emphasizes the criterion of aging, which affects the secretion of PTH by these cells, which in turn attenuates their osteogenic potential.

Keyphrases

stem cells
mesenchymal stem cells
bone marrow
induced apoptosis
cell therapy
cell cycle arrest
oxidative stress
cell death
quality improvement
sensitive detection
signaling pathway
endoplasmic reticulum stress
single molecule
quantum dots