Modern Dressings in Prevention and Therapy of Acute and Chronic Radiation Dermatitis-A Literature Review.
Konrad ZasadzińskiMateusz Jacek SpałekPiotr Lukasz RutkowskiPublished in: Pharmaceutics (2022)
Radiotherapy is an integral part of modern oncology, applied to more than half of all patients diagnosed with cancer. It can be used alone or in combination with surgery or chemotherapy. However, despite the high precision of radiation delivery, irradiation may affect surrounding healthy tissues leading to the development of toxicity. The most common and clinically significant toxicity of radiotherapy is acute and chronic radiation dermatitis, which could result in desquamation, wounds, nonhealing ulcers, and radionecrosis. Moreover, preoperative radiotherapy impairs wound healing after surgery and may lead to severe wound complications. In this review, we comprehensively discuss available types of dressings used in the management of acute and chronic radiation dermatitis and address their efficacy. The most effective ways of preventing acute radiation dermatitis are film dressings, whereas foam dressings were found effective in its treatment. Data regarding dressings in chronic radiation dermatitis are scarce. This manuscript also contains authors' consensus.
Keyphrases
- liver failure
- radiation induced
- drug induced
- respiratory failure
- early stage
- wound healing
- locally advanced
- radiation therapy
- aortic dissection
- atopic dermatitis
- end stage renal disease
- ejection fraction
- gene expression
- oxidative stress
- hepatitis b virus
- newly diagnosed
- chronic kidney disease
- stem cells
- early onset
- prognostic factors
- intensive care unit
- acute coronary syndrome
- bone marrow
- surgical site infection
- coronary artery disease
- extracorporeal membrane oxygenation
- replacement therapy
- smoking cessation
- electronic health record
- ionic liquid
- childhood cancer
- data analysis
- combination therapy