Arginine or Hypertonic Saline-Stimulated Copeptin to Diagnose AVP Deficiency.
Julie C RefardtCihan AtilaIrina ChifuEmanuele FerranteZoran ErlicJuliana B DrummondRita IndirliRoosmarijn C DrexhageClara Odilia SailerAndrea WidmerSusan FelderAndrew S PowlsonNina HutterDeborah R VogtMark GurnellBeatriz S SoaresJohannes HoflandFelix BeuschleinFassnacht MartinBettina WinzelerMirjam Christ-CrainPublished in: The New England journal of medicine (2024)
Among adult patients with polyuria polydipsia syndrome, AVP deficiency was more accurately diagnosed with hypertonic saline-stimulated copeptin than with arginine-stimulated copeptin. (Funded by the Swiss National Science Foundation; CARGOx ClinicalTrials.gov number, NCT03572166.).