ELN iMDS flow working group validation of the monocyte assay for chronic myelomonocytic leukemia diagnosis by flow cytometry.

Orianne Wagner-BallonPeter BettelheimJeroen LaufFrauke BellosMatteo Della PortaErica TravaglinoDolores SubiráIrene Nuevo LopezSihem TarfiTheresia M WestersUlrika JohanssonKatherina PsarraSerafeim KarathanosSergio MatarrazEnrique ColadoMonali GuptaRobin IrelandWolfgang KernArjan A Van De Loosdrechtnull null

Published in: Cytometry. Part B, Clinical cytometry (2021)

This ELN multicenter study demonstrates the robustness of the monocyte assay with only limited variability of cMo percentages, validates the 94% cutoff value, confirms its high sensitivity and specificity in PB and finally, also confirms the possibility of its use in BM samples.

Keyphrases

flow cytometry
dendritic cells
high throughput
endothelial cells
peripheral blood
acute myeloid leukemia
bone marrow
risk assessment
single cell