Frozen tissue coring and layered histological analysis improves cell type-specific proteogenomic characterization of pancreatic adenocarcinoma.

Sara R SavageYuefan WangLijun ChenScott JewellChelsea NewtonYongchao DouQing Kay LiOliver F BatheAna I RoblesGilbert S OmennMathangi ThiagarajanHui ZhangGalen HostetterBing Zhang

Published in: Clinical proteomics (2024)

Our study demonstrates the feasibility of multi-omics data generation from tissue cores, the necessity of interval H&E stains in serial histology sections, and the utility of coring to improve analysis over bulk tissue data.

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