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Comparative protective efficacy of a newly generated live recombinant thermostable highly attenuated vaccine rK148/GVII-F using a single regimen against lethal NDV GVII.1.1.

Amal Abdallah MouhamedJiho LeeDeok-Hwan KimChang-Seon Song
Published in: Avian pathology : journal of the W.V.P.A (2023)
A thermostable, safe, and effective NDV GVII recombinant vaccine was generated.Fusion gene replacement with GVII did not affect GI K148/08 virus thermostability.Strain rK148/GVII-F provided adequate protection against a lethal NDV challenge.Oropharyngeal shedding was significantly reduced on post-challenge days 5 and 7.
Keyphrases
  • cell free
  • genome wide
  • dna methylation