Genome-Wide Association Study of Treatment-Resistant Depression: Shared Biology With Metabolic Traits.

JooEun KangVictor M CastroMichael RippergerSanan VenkateshDavid BursteinRichard Karlsson LinnérDaniel B RochaYirui HuDrew WilimitisTheodore MorleyLide HanRachel Youngjung KimYen-Chen Anne FengTian GeStephan HeckersGeorgios VoloudakisChristopher ChabrisPanos RoussosThomas H McCoyColin G WalshRoy H PerlisDouglas M Ruderfer

Published in: The American journal of psychiatry (2024)

This work provides support for the utility of estimation of disease probability for genomic investigation and provides insights into the genetic architecture and biology of TRD.

Keyphrases

genome wide association study
genome wide
copy number
depressive symptoms
sleep quality
dna methylation
physical activity