Impact of preoperative chemotherapy on surgical results in 139 patients with locally advanced pancreatic cancer.
Marvin PetrikowskiTim FahlbuschAnke C Reinacher-SchickGiedre KucinskaiteAndrea TannapfelWaldemar UhlOrlin BelyaevPublished in: Hepatobiliary surgery and nutrition (2024)
This study underlines that PCT allows resectability of primarily unresectable patients with LAPC without increasing perioperative mortality and morbidity. It may lead to a significant prolongation of recurrence-free and overall survival in resected patients after PCT.
Keyphrases
- locally advanced
- rectal cancer
- end stage renal disease
- neoadjuvant chemotherapy
- squamous cell carcinoma
- prognostic factors
- patients undergoing
- chronic kidney disease
- newly diagnosed
- ejection fraction
- radiation therapy
- phase ii study
- free survival
- cardiovascular events
- cardiac surgery
- peritoneal dialysis
- risk factors
- clinical trial
- cardiovascular disease
- patient reported outcomes
- coronary artery disease
- acute kidney injury
- patient reported
- liver metastases
- chemotherapy induced