Fractionated small cell-free DNA increases possibility to detect cancer-related gene mutations in advanced colorectal cancer.
Yasuaki IshidaShinichi TakanoShinya MaekawaTatsuya YamaguchiTakashi YoshidaShoji KobayashiFumihiko IwamotoToru KunoHiroshi HayakawaShuya MatsudaMitsuharu FukasawaHiroko ShindoTaisuke InoueYasuhiro NakayamaDaisuke IchikawaTadashi SatoNobuyuki EnomotoPublished in: JGH open : an open access journal of gastroenterology and hepatology (2020)
Fractionated small cfDNA increased MAFs of gene mutations and increases the possibilities to detect cancer-related genes even in advanced cancer patients from whom it is difficult to obtain tissue samples.