BMI and cardiometabolic traits in Japanese: a Mendelian randomization study.
Mako NagayoshiAsahi HishidaTomonori ShimizuYasufumi KatoYoko KuboRieko OkadaTakashi TamuraJun OtonariHiroaki IkezakiMegumi HaraYuichiro NishidaIsao OzeYuriko N KoyanagiYohko NakamuraMiho KusakabeRie IbusukiKeiichi ShibuyaSadao SuzukiTakeshi NishiyamaTeruhide KoyamaEtsuko OzakiKiyonori KurikiNaoyuki TakashimaYasuyuki NakamuraSakurako Katsuura-KamaoKokichi ArisawaMasahiro NakatochiYukihide MomozawaKenji TakeuchiKenji WakaiPublished in: Journal of epidemiology (2023)
The results of this study suggest that, even among the Japanese, an East Asian population with low levels of obesity, higher BMI could be causally associated with the development of a variety of cardiometabolic traits. Causality in those associations should be clarified in future studies with larger populations, especially those of BMI with type 2 diabetes.