Complete Epstein-Barr virus seropositivity in a large cohort of patients with early multiple sclerosis.
Sargis AbrahamyanBettina EberspächerMuna-Miriam HoshiLilian AlyFelix LuessiSergiu GroppaLuisa KlotzSven G MeuthChristoph SchroederThomas GrüterBjörn TackenbergFriedemann PaulFlorian Then-BerghTania KümpfelFrank WeberMartin StangelAntonios BayasBrigitte WildemannChristoph HeesenUwe ZettlClemens WarnkeGisela AntonyNicole HesslerHeinz WiendlStefan BittnerBernhard HemmerRalf GoldSalmen AnkeKlemens Ruprechtnull nullnull nullPublished in: Journal of neurology, neurosurgery, and psychiatry (2020)
The complete EBV seropositivity in this large cohort of patients with early MS strengthens the evidence for a role of EBV in MS. It also suggests that a negative EBV serology in patients with suspected inflammatory central nervous system disease should alert clinicians to consider diagnoses other than MS.