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Contraction behaviour reduces embryo competence in high-quality euploid blastocysts.

Xavier Viñals GonzalezRabi OdiaSuzanne CawoodMatthew GauntWael SaabSvidrya SeshadriPaul Serhal
Published in: Journal of assisted reproduction and genetics (2018)
Most aneuploid blastocysts diagnosed by PGT-A have complex aneuploidies, showing that aneuploid embryos can develop after genomic activation and reaching high morphological scores. It becomes clear that embryo contraction, despite being a physiological feature during blastulation, is conditioned by the ploidy status of the embryo. Furthermore, the presence of contractions may compromise implantation rates.
Keyphrases
  • pregnancy outcomes
  • smooth muscle
  • machine learning
  • deep learning
  • copy number