Contraction behaviour reduces embryo competence in high-quality euploid blastocysts.
Xavier Viñals GonzalezRabi OdiaSuzanne CawoodMatthew GauntWael SaabSvidrya SeshadriPaul SerhalPublished in: Journal of assisted reproduction and genetics (2018)
Most aneuploid blastocysts diagnosed by PGT-A have complex aneuploidies, showing that aneuploid embryos can develop after genomic activation and reaching high morphological scores. It becomes clear that embryo contraction, despite being a physiological feature during blastulation, is conditioned by the ploidy status of the embryo. Furthermore, the presence of contractions may compromise implantation rates.