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Current Take on Systemic Sclerosis Patients' Vaccination Recommendations.

Giuseppe MurdacaGiovanni NoberascoDario OlobardiClaudio LunardiMatteo MauleLorenzo DelfinoMassimo TriggianiChiara CardamoneDevis BenfaremoGianluca MoronciniAngelo VaccaNicola SuscaSebastiano GangemiPaola QuattrocchiLaura SticchiGiancarlo IcardiAndrea Orsi
Published in: Vaccines (2021)
Systemic sclerosis (SSc) is a rare autoimmune inflammatory rheumatic disease. The prevalence of SSc ranges from 7 to 700 cases per million worldwide. Due to multiple organ involvement and constant inflammatory state, this group of patients presents an increased risk of infectious diseases. This paper aimed to gather the up-to-date evidence on vaccination strategies for patients with SSc and to be a useful tool for the prevention and management of infectious diseases. The authors conducted a scoping review in which each paragraph presents data on a specific vaccine's safety, immunogenicity, and efficacy. The work deals with the following topics: SARS-CoV-2, seasonal influenza, S. pneumoniae , HAV, HBV, HZV, N. meningitidis , H. influenzae , HPV, and diphtheria-tetanus-pertussis.
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