Microbiological and Molecular Features Associated with Persistent and Relapsing Staphylococcus aureus Prosthetic Joint Infection.
Irene Muñoz-GallegoMaría Ángeles Meléndez-CarmonaJaime Lora-TamayoCarlos Garrido-AllepuzFernando ChavesVirginia SebastiánEsther ViedmaPublished in: Antibiotics (Basel, Switzerland) (2022)
-caused relapse and persistence PJI is associated with bacterial phenotypical and genotypical adaptation. The main paths of adaptation were persistence in the intracellular compartment, and the loss of antibiotic resistance genes and variant acquisition, especially in genes encoding adhesins.
Keyphrases
- antibiotic resistance genes
- staphylococcus aureus
- wastewater treatment
- microbial community
- multiple sclerosis
- anaerobic digestion
- genome wide
- biofilm formation
- reactive oxygen species
- disease activity
- free survival
- single molecule
- genome wide identification
- systemic lupus erythematosus
- methicillin resistant staphylococcus aureus
- transcription factor
- candida albicans