Imaging features and clinical course of undifferentiated round cell sarcomas with CIC-DUX4 and BCOR-CCNB3 translocations.

Emily J BradyMeera HameedWilliam D TapSinchun Hwang

Published in: Skeletal radiology (2020)

CIC-DUX4 sarcomas often present as necrotic and hypermetabolic soft tissue masses while sarcomas with BCOR-CCNB3 translocations are vascular bone lesions with necrosis at imaging. CIC-DUX4 sarcomas are clinically more aggressive than BCOR-CCNB3 sarcomas.

Keyphrases

high grade
soft tissue
high resolution
clear cell
stem cells
magnetic resonance imaging
bone mineral density
mesenchymal stem cells
mass spectrometry
body composition
postmenopausal women