Ethyl Acetate Fraction of Hedyotis diffusa Willd Induces Apoptosis via JNK/Nur77 Pathway in Hepatocellular Carcinoma Cells.

Weimin NingNishan XuChunhong ZhouLifang ZouJingyu QuanHua YangZinbin LuHui Hui Cao Jun-Shan Liu

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

In conclusion, EHDW exerted the anti-HCC effect, which may be attributed to the activation of JNK/Nur77 pathway. This study supported the rationale of HDW as an HCC therapeutic agent.

Keyphrases

signaling pathway
cell death
induced apoptosis
clinical trial
ionic liquid
endoplasmic reticulum stress