Targeting eotaxin-1 and CCR3 receptor alleviates enteric neuropathy and colonic dysfunction in TNBS-induced colitis in guinea pigs.
R T FilipponeA M RobinsonV JovanovskaR StavelyV ApostolopoulosJ C BornsteinKulmira NurgaliPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2018)
This is the first study demonstrating that inhibition of CCR3-eotaxin axis alleviates enteric neuropathy and restores functional changes in the gut associated with TNBS-induced colitis.