Study on the Relationship and Predictive Value of First-Trimester Pregnancy-Associated Plasma Protein-A, Maternal Factors, and Biochemical Parameters in Gestational Diabetes Mellitus: A Large Case-Control Study in Southern China Mothers.
Jinhui CuiPing LiXinjuan ChenLing LiLiping OuyangZhaoran MengJianhui FanPublished in: Diabetes, metabolic syndrome and obesity : targets and therapy (2023)
A Low serum PAPP-A level in the first trimester is an independent risk factor for developing GDM later in pregnancy. However, it is not a good independent predictor although the predictive value of a low serum PAPP-A level increases when combined with maternal factors and biochemical markers.