Automated typing of red blood cell and platelet antigens from whole exome sequences.

William J LaneSunitha VegeHelen H MahChristine Lomas-FrancisMaria AguadRobin Smeland-WagmanChristopher KochJacqueline M KillianCubby L GardnerMauricio De CastroMatthew S LeboRichard Max Kaufman Robert C GreenConnie M Westhoffnull null

Published in: Transfusion (2019)

The automated bloodTyper software was modified for WES biases to allow for accurate RBC and PLT antigen typing. Such analysis could become a routing part of future WES efforts.

Keyphrases

red blood cell
deep learning
machine learning
high throughput
genetic diversity
high resolution
dendritic cells
current status
quality improvement
copy number
immune response
data analysis
gene expression
genome wide