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FAM110B Inhibits Non-Small Cell Lung Cancer Cell Proliferation and Invasion Through Inactivating Wnt/β-Catenin Signaling.

Menghua XieLin CaiJingduo LiJing ZhaoYingxue GuoZaiyu HouXiupeng ZhangHua TianAilin LiYuan Miao
Published in: OncoTargets and therapy (2020)
In summary, our results demonstrated that the overexpression of FAM110B restricts the proliferation and invasion of NSCLC cells by inhibiting Wnt/β-catenin signaling. Our study reveals the antitumor function of FAM110B in NSCLC and indicates that FAM110B is a potential therapeutic target.
Keyphrases
  • cell proliferation
  • small cell lung cancer
  • stem cells
  • induced apoptosis
  • advanced non small cell lung cancer
  • signaling pathway
  • single cell
  • cell cycle arrest
  • brain metastases