Interaction between apolipoprotein E genotype and hypertension on cognitive function in older women in the Nurses' Health Study.

Iris Y KimFrancine GrodsteinPeter KraftGary C CurhanKatherine C HughesHongyan HuangJae Hee KangDavid J Hunter

Published in: PloS one (2019)

Women with hypertension and at least one APOE e4 allele had worse average cognitive function compared with women without hypertension with the e3/3 genotype; this difference was amplified among APOE e4 allele carriers with untreated hypertension.

Keyphrases

blood pressure
healthcare
mental health
public health
polycystic ovary syndrome
pregnant women
risk assessment
metabolic syndrome
arterial hypertension
pregnancy outcomes
health promotion