Antithymocyte globulin induction therapy and myocardial complement deposition in pediatric heart transplantation.
Stephanie GhalebSamuel G WittekindHugo R MartinezJennifer KastenZhiqian GaoTricia HengeholdClifford ChinPublished in: Pediatric transplantation (2021)
C4d deposition is common on EMB up to 1 year post-pediatric cardiac transplant following ATG induction. This high rate of positive C4d staining in the absence of histologic AMR after ATG induction therapy must be accounted for in making clinical decisions regarding cardiac allograft rejection diagnosis and treatment.