Predicting Response to Radical Chemoradiotherapy with Circulating HPV DNA (cHPV-DNA) in Locally Advanced Uterine Cervix Cancer.
Susan LalondrelleJen LeeRosalind J CuttsIsaac Garcia MurillasNik MatthewsNicholas TurnerKevin HarringtonKatherine VroobelEmily MorettiShreerang A BhidePublished in: Cancers (2023)
These results demonstrate that the panHPV-detect test shows high sensitivity and specificity for detecting cHPV-DNA in plasma. The test has potential applications in assessment of the response to CRT and in monitoring for relapse, and these initial findings warrant validation in a larger cohort.