Routine serum biomarkers, but not dual-energy X-ray absorptiometry, correlate with cortical bone mineral density in children and young adults with chronic kidney disease.

Alexander D LalayiannisNicola J CrabtreeCharles Joseph FerroVarvara AskitiAndromachi MitsioniLorenzo BiassoniAmrit KaurManish D SinhaDavid C WheelerNeill D DuncanJoyce PopoolaDavid V MilfordJin LongMary Beth LeonardMary FewtrellRukshana Shroff

Published in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2021)

Taken together, routinely used biomarkers, PTH, ALP and Ca, but not DXA, are moderate predictors of cortical BMD. DXA is not clinically useful and should not be routinely performed in children and young adults with CKD 4-5D.

Keyphrases

dual energy
bone mineral density
chronic kidney disease
computed tomography
postmenopausal women
body composition
image quality
young adults
end stage renal disease
contrast enhanced
middle aged
magnetic resonance imaging
clinical practice
high intensity
mass spectrometry