Identification of potential common genetic modifiers of neurofibromas: a genome wide association study in 1,333 neurofibromatosis type 1 patients.
Laurence PacotAudrey SabbaghPierre SohierDjihad HadjadjManuela YeAnne Boland-AugeDelphine Bacq-DaianIngrid LaurendeauAudrey Briand-SuleauJean François DeleuzeRaphaël MargueronMichel VidaudSalah FerkalBéatrice ParfaitDominique Vidaudnull nullÉric PasmantPierre WolkensteinPublished in: The British journal of dermatology (2023)
Our study may shed new light on the pathogenesis of NF1-associated neurofibromas and will hopefully contribute to the development of personalized care for this deleterious and life-threatening condition.
Keyphrases
- genome wide association study
- end stage renal disease
- ejection fraction
- chronic kidney disease
- healthcare
- signaling pathway
- palliative care
- peritoneal dialysis
- prognostic factors
- oxidative stress
- risk assessment
- quality improvement
- lps induced
- pain management
- patient reported outcomes
- inflammatory response
- human health