Epidemiological and Antimicrobial Resistant Patterns, and Molecular Mechanisms of Carbapenem-Resistant Klebsiella pneumoniae Infections in ICU Patients.
Fanbo LuLuwen ZhangJuanjuan JiYuanhong XuBo WangJinxing XiaPublished in: Infection and drug resistance (2023)
infections among ICU patients. The CRKP cohort exhibited substantially high antimicrobial resistance. Distinctive carbapenemase-, virulence-, and serotype-associated genes were intensively involved in the spread and pathogenesis of CRKP. These findings supported careful management of critically ill patients potentially infected with virulent CRKP in the ICUs.
Keyphrases
- klebsiella pneumoniae
- antimicrobial resistance
- end stage renal disease
- ejection fraction
- chronic kidney disease
- multidrug resistant
- newly diagnosed
- intensive care unit
- staphylococcus aureus
- patient reported outcomes
- pseudomonas aeruginosa
- gram negative
- acinetobacter baumannii
- gene expression
- drug resistant
- zika virus
- acute respiratory distress syndrome
- cystic fibrosis
- aedes aegypti
- transcription factor