Evaluation of urinary FOXP3 mRNA as a biomarker of lupus nephritis in Egyptian patients with systemic lupus erythematosus.

Ahmed FayedAbdelAal MohamedReham Abdelghany AhmedSameh AbouzeidAhmed SolimanAhmed Fathy

Published in: Lupus (2021)

We concluded that urinary FOXP3 mRNA is elevated in patients with active LN and that it is linked to the SLEDAI and the severity of the disease. FOXP3 mRNA in urine sediment may be used as a non-invasive biomarker for evaluating the severity of LN and risk stratification.

Keyphrases

regulatory t cells
binding protein
dendritic cells
heavy metals
risk assessment
polycyclic aromatic hydrocarbons