Direct Synthesis of ortho-Halogenated Arylphosphonates via a Three-Component Reaction Involving Arynes.

A three-component reaction involving arynes, trialkyl phosphites, and halides has been achieved under mild reaction conditions. This transformation provides a direct synthetic approach to ortho-halogenated arylphosphonates, which could be rapidly converted to diversely ortho-functionalized arylphosphorus compounds.