Identification of S419 on human serum albumin as a novel biomarker for sarin and cyclosarin exposure.

Feiyan FuHaibo Liu Xiaogang LuRuihua ZhangLiqin LiRunli GaoJianwei XieHongmei WangChengxin Pei

Published in: Rapid communications in mass spectrometry : RCM (2021)

This research revealed a new site, S419, of the tryptic peptide KVPQVSTPTLVEVSR on human albumin to be a valuable biomarker for sarin/cyclosarin exposure, helping to further distinguish sarin and cyclosarin poisoning from that of other nerve agents and providing an important tool for the identification of sarin or cyclosarin in terrorist attacks.

Keyphrases

human serum albumin
endothelial cells
bioinformatics analysis
single cell
peripheral nerve