Impact of induction regimens intensity and allogeneic stem cell transplantation on survival of patients with Philadelphia chromosome-positive acute lymphoblastic leukemia: A multi-institutional study.
Talha BadarRavi NarraAlice S MimsMichael G HeckmanRory M ShallisSheikh FahadCameron HunterVamsi K KotaTamer Adel OthmanBrian A JonasShreya DesaiGuilherme Sacchi de Camargo CorreiaAnand Ashwin PatelAdam S DuVallNeil PalmisianoEmily CurranZulfa OmerAnjali S AdvaniEhab AtallahMark R LitzowPublished in: American journal of hematology (2024)
Intensive chemotherapy (IC) combination with second- or third-generation TKI improves survival compared to non-IC with first-generation TKI. Allo-HCT was suggestive of improving RFS/OS after propensity score matching and multivariable analysis.
Keyphrases
- stem cell transplantation
- acute lymphoblastic leukemia
- high dose
- tyrosine kinase
- chronic myeloid leukemia
- allogeneic hematopoietic stem cell transplantation
- advanced non small cell lung cancer
- free survival
- low dose
- bone marrow
- epidermal growth factor receptor
- dna methylation
- cell proliferation
- signaling pathway
- hematopoietic stem cell
- pi k akt