Single-cell RNA-seq analysis identifies meniscus progenitors and reveals the progression of meniscus degeneration.

Hao SunXingzhao WenHongyi LiPeihui WuMinghui GuXiaoyi ZhaoZiji ZhangShu HuGuping MaoRuofan MaWeiming LiaoZhiqi Zhang

Published in: Annals of the rheumatic diseases (2019)

The identification of meniscus progenitor cells provided new insights into cell-based meniscus tissue engineering, demonstrating a novel mechanism of meniscus degeneration, which contributes to the development of a novel therapeutic strategy.

Keyphrases

single cell
rna seq
anterior cruciate ligament
anterior cruciate ligament reconstruction
tissue engineering
high throughput
stem cells
cell therapy
gene expression
data analysis