Specific Blood RNA Profiles in Individuals with Acute Spinal Cord Injury as Compared with Trauma Controls.

Qing Chen Longqing Wang Hao Wu Cheng Ye Dong Xie Qi Zhao Qi Zhu Chenhui Xu Lili Yang

Published in: Oxidative medicine and cellular longevity (2023)

The specific hub genes of acute SCI as compared with trauma without CNS injury were identified. The functional enrichment analysis of hub genes showed a specific immune response. Several predicted drugs of hub genes were also obtained. The hub genes and the predicted miRNAs may be potential biomarkers and therapeutic targets and require further validation.

Keyphrases

bioinformatics analysis
spinal cord injury
genome wide
immune response
liver failure
network analysis
genome wide identification
respiratory failure
drug induced
spinal cord
blood brain barrier
gene expression
toll like receptor
inflammatory response
transcription factor