Influence of Lipoxygenase Inhibition on Glioblastoma Cell Biology.
Felipe da Costa SouzaMatthew Thomas FerreiraAlison ColquhounPublished in: International journal of molecular sciences (2020)
15-LOX and its linoleic acid (LA)-derived metabolites exercise a protumorigenic influence on GBM cells in vitro. Elevated endogenous levels of 13-HODE called attention to the relationship between linoleic acid metabolism and GBM cell activity.