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Properly Collected Plasma Metanephrines Excludes PPGL After False-Positive Screening Tests.

Gregory A KlineJessica BoydBrenda PolzinAdrian HarveyJanice L PasiekaHossein S M SadrzadehAlexander A Leung
Published in: The Journal of clinical endocrinology and metabolism (2021)
There was a poor-to-moderate correlation between urine and seated plasma metanephrines. Up to 20% of those with high urine measures also had high seated plasma metanephrines in the absence of PPGL. Properly prepared and collected supine plasma metanephrines had a false-positive rate of <3% in the absence of known PPGL/adrenal mass.
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