Phenotypic and genotypic drug susceptibility patterns of Mycobacterium tuberculosis isolates from pulmonary tuberculosis patients in Central and Southern Ethiopia.

Melaku TilahunTeklu WegayehuBiniam WondaleTewdros Tariku GebresilaseTesfaye GebreyohannesAbraham TekolaMekdes AlemuSebsibe NewayBethlehem AdnewMaeruf Fetu NassirYonas KassahunAbraham AseffaKidist Bobosha

Published in: PloS one (2023)

This study reveals a higher prevalence of phenotypic and genotypic discordant INH-resistant M. tuberculosis isolates in the study area. The use of whole-genome sequencing (WGS) is essential for gaining a comprehensive understanding of these discrepancies within INH-resistant M. tuberculosis strains.

Keyphrases

mycobacterium tuberculosis
pulmonary tuberculosis
end stage renal disease
escherichia coli
ejection fraction
chronic kidney disease
prognostic factors
adverse drug
peritoneal dialysis
patient reported