Intratumoral Heterogeneity and Immune Modulation in Lung Adenocarcinoma in Female Smokers and Never Smokers.

Timo B Trefzer Marc A Schneider Katharina Jechow Robert Lorenz ChuaThomas MuleyHauke WinterMark KriegsmannMichael MeisterRoland EilsChristian Conrad

Published in: Cancer research (2022)

Single-cell analysis of healthy lung tissue and lung cancer reveals distinct tumor cell populations, including cells with differential immune modulating capacity between smokers and never smokers, which could guide future therapeutic strategies.

Keyphrases

single cell
smoking cessation
rna seq
induced apoptosis
high throughput
signaling pathway
cell cycle arrest
cell therapy
cell proliferation