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Activin A levels in metabolic dysfunction-associated steatotic liver disease associates with fibrosis and the PNPLA3 I148M variant.

Cecilia JönssonMartin BergramStergios KechagiasPatrik NasrMattias Ekstedt
Published in: Scandinavian journal of gastroenterology (2024)
I148M G/G had higher levels of activin A proposing activin A as a contributor of the transition from simple steatosis to a fibrotic phenotype.
Keyphrases
  • insulin resistance
  • oxidative stress
  • high fat diet
  • systemic sclerosis
  • type diabetes
  • idiopathic pulmonary fibrosis
  • adipose tissue