Efficient [(NHC)Au(NTf2)]-catalyzed hydrohydrazidation of terminal and internal alkynes.

Published in: Beilstein journal of organic chemistry (2020)

The efficient hydrohydrazidation of terminal (6a-r, 18 examples, 0.1-0.2 mol % [(NHC)Au(NTf2)], T = 60 °C) and internal alkynes (7a-j, 10 examples, 0.2-0.5 mol % [(NHC)Au(NTf2)], T = 60-80 °C) utilizing a complex with a sterically demanding bispentiptycenyl-substituted NHC ligand and the benign reaction solvent anisole, is reported.

Keyphrases

sensitive detection
reduced graphene oxide
molecular docking
room temperature
ionic liquid
visible light
quantum dots
molecular dynamics simulations