G-protein coupled receptor 34 regulates the proliferation and growth of LS174T cells through differential expression of PI3K subunits and PTEN.
Bo ZuoNa WuShen YangZhaohui ZhongMei LiXin YuYulan LiuWeidong YuPublished in: Molecular biology reports (2022)
Our findings provide direct evidence that GPR34 regulates the proliferation of LS174T cells and the growth of LS174T tumor xenografts by regulating different pathways. High expression of GPR34 mRNA could then be used to predict poor prognosis of CRC.