Celsr3 drives development and connectivity of the acoustic startle hindbrain circuit.
Joy H MeserveMaria F NavarroElelbin A OrtizMichael GranatoPublished in: bioRxiv : the preprint server for biology (2024)
The PCP cadherin Celsr3 regulates startle circuit development in zebrafishCelsr3 and other PCP-associated proteins promote Mauthner axon growth and guidanceCelsr3 is required for spiral fiber and glia targeting to the Mauthner axon capSymmetric spiral fiber input to Mauthners is critical for escape direction.