The burden of depressive disorders in musculoskeletal diseases: is there an association between mood and inflammation?
Maria Sole ChimentiGiulia Lavinia FontiPaola ConigliaroPaola TriggianeseEmanuela BianciardiMarialuce CovielloGinevra LombardozziGiulia TarantinoCinzia NioluAlberto SiracusanoRoberto PerriconePublished in: Annals of general psychiatry (2021)
The main causes of the variability in clinical studies outcomes are the rheumatological diseases considered, the prevalence of depression in the general population and in patients with rheumatological diseases and the type of depressive symptom examined. Patients affected by inflammatory arthritis can present symptoms and signs in common with mood disorders, leading to possible clinical overlap. There are still few studies analyzing this concept: they are extremely heterogeneous, both in the characteristics of the population taken into consideration and in the methods used for the definition of depressive disorder, but the suggestions of the data obtained so far are promising and deserve to be pursued.
Keyphrases
- bipolar disorder
- sleep quality
- end stage renal disease
- oxidative stress
- stress induced
- ejection fraction
- newly diagnosed
- chronic kidney disease
- risk factors
- rheumatoid arthritis
- prognostic factors
- depressive symptoms
- peritoneal dialysis
- type diabetes
- big data
- machine learning
- insulin resistance
- metabolic syndrome
- skeletal muscle