Stereotactic Radiotherapy: An Alternative Option for Refractory Ventricular Tachycardia to Drug and Ablation Therapy.
Wenfeng ShangguanGang XuXin WangNan ZhangXingpeng LiuGuangping LiGary TseTong LiuPublished in: Journal of clinical medicine (2022)
Refractory ventricular tachycardia (VT) often occurs in the context of organic heart disease. It is associated with significantly high mortality and morbidity rates. Antiarrhythmic drugs and catheter ablation represent the two main treatment options for refractory VT, but their use can be associated with inadequate therapeutic responses and procedure-related complications. Stereotactic body radiotherapy (SBRT) is extensively applied in the precision treatment of solid tumors, with excellent therapeutic responses. Recently, this highly precise technology has been applied for radioablation of VT, and its early results demonstrate a favorable safety profile. This review presents the potential value of SBRT in refractory VT.
Keyphrases
- catheter ablation
- radiation therapy
- atrial fibrillation
- early stage
- left atrial
- locally advanced
- risk factors
- radiation induced
- left atrial appendage
- small cell lung cancer
- type diabetes
- cardiovascular events
- pulmonary hypertension
- risk assessment
- rectal cancer
- bone marrow
- drug induced
- brain metastases
- left ventricular
- human health
- replacement therapy
- radiofrequency ablation