Psilocybin mitigates the cognitive deficits observed in a rat model of Fragile X syndrome.
Valeria BuzzelliEmilia CarboneAntonia ManducaSara SchiaviAlessandro FeoJulia V PerederiyKyle H AmbertMarvin HausmanViviana TrezzaPublished in: Psychopharmacology (2022)
These data support the hypothesis that serotonin-modulating drugs such as psilocybin may be useful to ameliorate ASD-related cognitive deficits. Overall, this study provides evidence of the beneficial effects of different schedules of psilocybin treatment in mitigating the short-term cognitive deficit observed in a rat model of FXS.