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Increased biological relevance of transcriptome analyses in human skeletal muscle using a model-specific pipeline.

Yusuf KhanDaniel HammarströmBent R RønnestadStian EllefsenRafi Ahmad
Published in: BMC bioinformatics (2020)
Optimized selection of bioinformatic tools increases the biological relevance of transcriptome analyses from resistance-trained skeletal muscle. Moreover, normalization procedures need to account for global changes in rRNA and mRNA abundance.
Keyphrases
  • skeletal muscle
  • rna seq
  • insulin resistance
  • single cell
  • genome wide
  • endothelial cells
  • gene expression
  • induced pluripotent stem cells
  • dna methylation
  • type diabetes
  • adipose tissue