Login / Signup

Highly regioselective α-formylation and α-acylation of BODIPY dyes via tandem cross-dehydrogenative coupling with in situ deprotection.

Fan LvYang YuErhong HaoChangjiang YuHua WangNoёl BoensLijuan Jiao
Published in: Organic & biomolecular chemistry (2019)
A metal-free C-H formylation and acylation of BODIPY dyes using a variety of dioxolane derivatives as aldehyde equivalents is reported, providing a postfunctionalization method for controllable synthesis of BODIPYs with carbonyl groups at 3,5-positions via a radical process. The photophysical properties of resultant dyes from this efficient one-pot, chemo- and site-selective transformation have been studied.
Keyphrases
  • fluorescent probe
  • aqueous solution
  • living cells
  • photodynamic therapy
  • squamous cell carcinoma
  • radiation therapy
  • locally advanced
  • drug delivery
  • rectal cancer
  • ionic liquid