A Multifunctional Nano-Delivery System Against Rheumatoid Arthritis by Combined Phototherapy, Hypoxia-Activated Chemotherapy, and RNA Interference.
Xiangyu LiShixin ZhangMiaomiao ZhangGe LiBo YangXinyue LuLesheng TengYouxin LiFengying SunPublished in: International journal of nanomedicine (2022)
Overall, these FA-functionalized, pH-responsive PFHNs/TM represent a promising platform for the co-delivery of chemical drugs and nucleic acids for the treatment of RA cooperating with NIR-induced phototherapy.
Keyphrases
- rheumatoid arthritis
- disease activity
- high glucose
- drug delivery
- endothelial cells
- ankylosing spondylitis
- interstitial lung disease
- photodynamic therapy
- high throughput
- diabetic rats
- quantum dots
- systemic lupus erythematosus
- squamous cell carcinoma
- locally advanced
- cancer therapy
- radiation therapy
- fluorescent probe
- molecularly imprinted
- fluorescence imaging
- mass spectrometry
- idiopathic pulmonary fibrosis
- stress induced