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Paraoxonase-1 Serum Concentration and PON1 Gene Polymorphisms: Relationship with Non-Alcoholic Fatty Liver Disease.

Mircea-Vasile MilaciuȘtefan-Cristian VesaIoana Corina BocșanLorena CiumărneanDorel SâmpeleanVasile NegreanRaluca-Maria PopDaniela Maria MateiSergiu PașcaAndreea Liana RăchișanAnca Dana BuzoianuMonica Acalovschi
Published in: Journal of clinical medicine (2019)
PON1 serum concentrations were diminished in patients with NAFLD, and the presence of NAFLD was linked with low PON1 concentration. The LM + MM genotypes of the PON1 L55M polymorphism were an independent predictor for NAFLD with persistently elevated aminotransferases.
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