Efficacy of a Hybrid Closed-Loop Solution in Patients With Excessive Time in Hypoglycaemia: A Post Hoc Analysis of Trials With DBLG1 System.

Pierre Yves BenhamouAlice AdenisYousra TourkiSylvie PouStéphanie MadrolleSylvia FrancDulanjalee KariyawasamJacques BeltrandDavid C KlonoffGuillaume Charpentier

Published in: Journal of diabetes science and technology (2022)

DBLG1 decreased time in hypoglycaemia by more than 50% even in patients with excessive time in hypoglycaemia at baseline, while also improving both TIR and GRI, under real-life conditions. The improvement in GRI (13.2%) exceeded that of the improvement in TIR (5.1%) indicating that in this data set, GRI was more sensitive than TIR to the improvement in glycaemia achieved with closed-loop. These results support the safety and efficacy of this treatment.

Keyphrases

type diabetes
weight gain
physical activity
machine learning
weight loss
smoking cessation